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規(guī)格	庫(kù)存	目錄價(jià)	會(huì)員專享價(jià)	數(shù)量
10 mg	In-stock	￥766.00	登錄后可見	- +
20 mg	In-stock	￥1306.00	登錄后可見	- +
50 mg	3-5days	￥2406.00	登錄后可見	- +

規(guī)格

庫(kù)存

目錄價(jià)

會(huì)員專享價(jià)

數(shù)量

10 mg

In-stock

￥766.00

登錄后可見

- +

20 mg

In-stock

￥1306.00

登錄后可見

- +

50 mg

3-5days

￥2406.00

登錄后可見

- +

基本信息

英文名稱	Brefeldin A (Synonyms: BFA ; Cyanein ; Decumbin)
中文名稱	(1R,2E,6S,10E,11AS,13S,14aR)-1,13二羥基-6-甲基6,7,8,9,12,13,14,14a-八氫-1H-環(huán)戊二烯并[f][1]氧雜環(huán)十三烷-4(11aH)-酮; 布雷菲德菌素A
CAS號(hào)	20350-15-6
分子式	C16H24O4
分子量	280.36
MDL	MFCD00083258
外觀	Off-white powder
儲(chǔ)存條件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

產(chǎn)品詳情

Brefeldin A (BFA) is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells, induces cancer cell differentiation and apoptosis. It could also improve the HDR(homology-directed repair) efficiency and be an enhancer of CRISPR-mediated HDR. Brefeldin A is also an inhibitor of autophagy and mitophagy.

相關(guān)文獻(xiàn)

Brefeldin A reduces anchorage-independent survival, cancer stem cell potential and migration of MDA-MB-231 human breast cancer cells.

2014 Oct 29;19(11):17464-77.

PMID: 27091640 PMCID: PMC4835698 DOI: 10.1038/srep24641

PMID: 23716697 PMCID: PMC3683763 DOI: 10.1073/pnas.1222413110

PMID: 25658371 PMCID: PMC4461869 DOI: 10.1016/j.stem.2015.01.003

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CL1001

(1R,2E,6S,10E,11AS,13S,14aR)-1,13二羥基-6-甲基6,7,8,9,12,13,14,14a-八氫-1H-環(huán)戊二烯并[f][1]氧雜環(huán)十三烷-4(11aH)-酮; 布雷菲德菌素A