| 英文名稱 | Cediranib | ADZ-2171 | NSC-732208 |
|---|---|
| 中文名稱 | 西地尼布 |
| CAS號 | 288383-20-0 |
| 分子式 | C25H27FN4O3 |
| 分子量 | 450.51 |
| 外觀 | White to yellow powder |
| 儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
| 英文名稱 | Cediranib | ADZ-2171 | NSC-732208 |
|---|---|
| 中文名稱 | 西地尼布 |
| CAS號 | 288383-20-0 |
| 分子式 | C25H27FN4O3 |
| 分子量 | 450.51 |
| 外觀 | White to yellow powder |
| 儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Cediranib (AZD2171) is a highly potent, orally available VEGFR tyrosine kinase inhibitor with IC50s of <1, <3, 5, 5, 36, 2 nM for Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit, respectively.
PMID: 15899831 DOI: 10.1158/0008-5472.CAN-04-4409
PMID: 26645582 DOI: 10.1126/scisignal.aaa1690