英文名稱 | PNU-159682 (Synonyms: PNU 159682) |
---|---|
中文名稱 | PNU-159682; PNU 159682 |
CAS號 | 202350-68-3 |
分子式 | C32H35NO13 |
分子量 | 641.62 |
英文名稱 | PNU-159682 (Synonyms: PNU 159682) |
---|---|
中文名稱 | PNU-159682; PNU 159682 |
CAS號 | 202350-68-3 |
分子式 | C32H35NO13 |
分子量 | 641.62 |
PNU-159682, a metabolite of the anthracycline Nemorubicin, is a highly potent DNA topoisomerase II inhibitor with excellent cytotoxicity. PNU-159682 acts as a more potent and tolerated ADC cytotoxin than Doxorubicin for ADC synthesis. PNU-159682 can be used in EDV-nanocell technology to overcome agent resistance.