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規(guī)格	庫存	目錄價	會員專享價	數(shù)量
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規(guī)格

庫存

目錄價

會員專享價

數(shù)量

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基本信息

英文名稱	Sivelestat \| EI546 \| LY544349 \| ONO5046
中文名稱	西維來司他
CAS號	127373-66-4
分子式	C20H22N2O7S
分子量	434.46
外觀	White to off-white powder
儲存條件	4°C, protect from light

產(chǎn)品詳情

Sivelestat (EI546) is a competitive inhibitor of human neutrophil elastase, with an IC₅₀ of 44 nM and a K_i of 200 nM. Sivelestat (EI546) has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19.

相關(guān)文獻

A neutrophil elastase inhibitor, sivelestat, ameliorates lung injury after hemorrhagic shock in rats.

PMID: 17203197

Neutrophil elastase inhibitor, sivelestat sodium hydrate prevents ischemia-reperfusion injury in the rat bladder.

PMID: 18165924 DOI: 10.1007/s11010-007-9698-9

Neutrophil elastase inhibitor (sivelestat) may be a promising therapeutic option for management of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19.

PMID: 32860252 DOI: 10.1111/jcpt.13251

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