| 英文名稱 | GSK583 |
|---|---|
| 中文名稱 | GSK583 |
| CAS號 | 1346547-00-9 |
| 分子式 | C20H19FN4O2S |
| 分子量 | 398.45 |
| 外觀 | Light yellow to yellow powder |
| 儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
| 英文名稱 | GSK583 |
|---|---|
| 中文名稱 | GSK583 |
| CAS號 | 1346547-00-9 |
| 分子式 | C20H19FN4O2S |
| 分子量 | 398.45 |
| 外觀 | Light yellow to yellow powder |
| 儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
GSK583 is a highly potent and selective inhibitor of RIP2 kinase with IC50 of 5 nM. GSK583 also inhibits both TNF-α and IL-6 production with IC50 of ~200 nM in explant cultures.