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規(guī)格

庫存

目錄價(jià)

會(huì)員專享價(jià)

數(shù)量

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基本信息

英文名稱	Secalciferol (Synonyms: (24R)-24,25-Dihydroxyvitamin D3)
中文名稱	(3R,6R)-6-((1R,3aS,7aR,E)-4-((Z)-2-((S)-5-羥基-2-亞甲基亞環(huán)己基)亞乙基)-7a-甲基八氫-1H-茚-1-基)-2-甲基庚烷-2,3-二醇; 司骨化醇
CAS號(hào)	55721-11-4
分子式	C??H??O?
分子量	416.64
MDL	MFCD00941417
外觀	White to off-white powder
儲(chǔ)存條件	-20°C, protect from light, stored under nitrogen

產(chǎn)品詳情

Secalciferol, also known as (24R)-24,25-Dihydroxyvitamin D3, is the primary active form of Vitamin D. This compound potently activates the vitamin D receptor (VDR) with an EC50 value of 150 nM. It plays a crucial role in various biological processes, including the regulation of calcium homeostasis, cellular differentiation, and proliferation. Additionally, Secalciferol has significant implications for the immune system, making it a promising area of research for conditions such as rickets, osteomalacia, hypercalcemia, and autoimmune disorders.

This product is unstable in solution state. We recommend that you use it immediately.

相關(guān)文獻(xiàn)

Profiling of Vitamin D Metabolic Intermediates toward VDR Using Novel Stable Gene Reporter Cell Lines IZ-VDRE and IZ-CYP24[J].

PMID: 27327272 DOI: 10.1021/acs.chemrestox.6b00170

PMID: 10498030 DOI: 10.1016/s0039-128x(99)00057-4

J Toxicol Sci. 1999 May;24(2):133-9.

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