| 英文名稱 | ABT-888(Veliparib) |
|---|---|
| 中文名稱 | 維利帕尼 |
| CAS號 | 912444-00-9 |
| 分子式 | C13H16N4O |
| 分子量 | 244.29 |
| 外觀 | White solid |
| 儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
| 英文名稱 | ABT-888(Veliparib) |
|---|---|
| 中文名稱 | 維利帕尼 |
| CAS號 | 912444-00-9 |
| 分子式 | C13H16N4O |
| 分子量 | 244.29 |
| 外觀 | White solid |
| 儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Veliparib (ABT-888, NSC 737664) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively. It is inactive to SIRT2. Veliparib increases autophagy and apoptosis. Phase 3.