英文名稱(chēng) | Pirfenidone (AMR69) |
---|---|
中文名稱(chēng) | 吡非尼酮 |
CAS號(hào) | 53179-13-8 |
分子式 | C12H11NO |
分子量 | 197.33 |
外觀(guān) | White to light yellow powder |
儲(chǔ)存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
規(guī)格 | 庫(kù)存 | 目錄價(jià) | 會(huì)員專(zhuān)享價(jià) | 數(shù)量 |
---|---|---|---|---|
500 mg | In-stock | ¥480.00 | 登錄后可見(jiàn) | |
1 g | In-stock | ¥680.00 | 登錄后可見(jiàn) |
英文名稱(chēng) | Pirfenidone (AMR69) |
---|---|
中文名稱(chēng) | 吡非尼酮 |
CAS號(hào) | 53179-13-8 |
分子式 | C12H11NO |
分子量 | 197.33 |
外觀(guān) | White to light yellow powder |
儲(chǔ)存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Pirfenidone is an anti-fibrotic drug for the treatment of idiopathic pulmonary fibrosis (IPF). It works by reducing lung fibrosis through downregulation of the production of growth factors and procollagens I and II. Pirfenidone has well-established antifibrotic and anti-inflammatory properties in various in vitro systems and animal models of fibrosis. A number of cell-based studies have shown that pirfenidone reduces fibroblast proliferation, inhibits TGF-β stimulated collagen production and reduces the production of fibrogenic mediators such as TGF-β.