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吡非尼酮

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Pirfenidone (AMR69)

產(chǎn)品編號(hào):CL2376 CAS No.:53179-13-8 MDLNo: 分子式:C12H11NO 分子量:197.33
規(guī)格 庫(kù)存 目錄價(jià) 會(huì)員專(zhuān)享價(jià) 數(shù)量
500 mg In-stock ¥480.00 登錄后可見(jiàn)
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1 g In-stock ¥680.00 登錄后可見(jiàn)
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基本信息
英文名稱(chēng) Pirfenidone (AMR69)
中文名稱(chēng)吡非尼酮
CAS號(hào)53179-13-8
分子式C12H11NO
分子量197.33
外觀(guān)White to light yellow powder
儲(chǔ)存條件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
產(chǎn)品詳情

Pirfenidone is an anti-fibrotic drug for the treatment of idiopathic pulmonary fibrosis (IPF). It works by reducing lung fibrosis through downregulation of the production of growth factors and procollagens I and II. Pirfenidone has well-established antifibrotic and anti-inflammatory properties in various in vitro systems and animal models of fibrosis. A number of cell-based studies have shown that pirfenidone reduces fibroblast proliferation, inhibits TGF-β stimulated collagen production and reduces the production of fibrogenic mediators such as TGF-β.

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