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規(guī)格	庫(kù)存	目錄價(jià)	會(huì)員專享價(jià)	數(shù)量
2 mg	3-5days	￥1586.00	登錄后可見	- +
5 mg	3-5days	￥2586.00	登錄后可見	- +

規(guī)格

庫(kù)存

目錄價(jià)

會(huì)員專享價(jià)

數(shù)量

2 mg

3-5days

￥1586.00

登錄后可見

- +

5 mg

3-5days

￥2586.00

登錄后可見

- +

基本信息

英文名稱	RMC-7977
中文名稱	RMC-7977
CAS號(hào)	2765082-12-8
分子式	C47H60N8O6S
分子量	865.09
外觀	White to light yellow powder
儲(chǔ)存條件	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

產(chǎn)品詳情

RMC-7977 is a potent, reversible, tri-complex oral inhibitor that selectively targets active (GTP-bound) forms of KRAS, HRAS, and NRAS, which exhibits broad-spectrum activity against both mutant and wild-type variants (a RAS^MULTI (ON) inhibitor). It also exhibits significant anti-tumor efficacy in pancreatic ductal adenocarcinoma (PDAC).

相關(guān)文獻(xiàn)

RAS MULTI (ON) inhibitor RMC-7977 targets oncogenic RAS mutations and overcomes RAS/MAPK-mediated resistance to FLT3 inhibitors in AML models

https://doi.org/10.1182/blood-2023-178397

PMID: 38588697 PMCID: PMC11111406 DOI: 10.1038/s41586-024-07379-z

https://doi.org/10.21203/rs.3.rs-3122478/v1 PPR: PPR688102

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瀏覽記錄

CL2790

RMC-7977

2765082-12-8 98+% 3-5days

￥1586.00 2 mg

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RMC-7977

RMC-7977

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