英文名稱 | Anti-Human CD3xCD20 Bispecific Antibody (Mosunetuzumab; BTCT-4465A; R07030816;CD20-TDB; RG7828; CD20 CD3 bispecific antibody.) |
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中文名稱 | 莫妥珠單抗 |
CAS號 | 1905409-39-3 |
儲存條件 | store at -20°C |
英文名稱 | Anti-Human CD3xCD20 Bispecific Antibody (Mosunetuzumab; BTCT-4465A; R07030816;CD20-TDB; RG7828; CD20 CD3 bispecific antibody.) |
---|---|
中文名稱 | 莫妥珠單抗 |
CAS號 | 1905409-39-3 |
儲存條件 | store at -20°C |
Mosunetuzumab is a humanized bispecific antibody that targets CD20 on B cells and CD3 on T cells, redirecting T-cell cytotoxicity to kill malignant B cells. This IgG1 TDB antibody is being studied for treating relapsed/refractory B-cell non-Hodgkin lymphomas.
PMID: 34914545 PMCID: PMC8824395 DOI: 10.1200/JCO.21.00931
PMID: 29351372 PMCID: PMC5944627 DOI: 10.1111/cts.12535